A study aimed toward the patterns of expression of monocytes in patients with unstable angina, a disease that is part of spectrum of CAD, reported that HSP60 is expressed under stress conditions where correct blood flow is hindered to the myocardial tissue, and induces IL‐12p70 secretion by intermediate monocytes, a subset involved in antigen presentation.125. This evidence concerns the gene HSPD1 and coronary artery disorder.