Oral immunization using peptides from HSP60 together with some from other atherosclerosis‐related antigens such as oxLDL and ApoB‐100 have also been tested demonstrating effective induction of tolerance featuring the cellular and molecular hallmarks aforementioned; moreover multi‐antigenic vaccines using more than two antigenic sources are yet another take on tolerization that is being explored in the search for higher specificity responses.197, 198. This evidence concerns the gene APOB and atherosclerosis.