HSPD1 and rheumatoid arthritis: In some experimental studies regarding the repressing nature of T cells toward self‐HSP60 in rheumatoid arthritis, it has been demonstrated that recognition of certain self‐epitopes of HSP60 leads to the production of suppressive cytokines by regulatory type 2 cells such as TGF‐β and IL‐4 accompanied by a decreased production of IL‐2 and proliferation in contrast with the recognition of mycobacterial HSP60, where T cells showed greater reactivity and cytokine production.81