CD4 and cancer: The percentage of cancer cells was positively correlated with the percentage of CD8+ T cells (r = 0.6025, p = 0.0174), Tregs (r = 0.5317, p = 0.0436), and negatively correlated with the percentage of CD4+ T cells (r = − 0.5989, p = 0.0303 (Supplementary Figure 3).