MKI67 and neoplasm: Quantification of H&E staining of lung sections from cisplatin-treated animals who received nanoplex-siMK2 demonstrated a six-fold reduction in tumor burden and Ki67 staining compared to control siRNA nanoplex-treated animals (Fig. 3l, m), indicating reduced proliferation in tumors treated with the combination of nanoplex–siMK2 and cisplatin.