Mice bearing separate tumours from both cell lines were randomly assigned to (1) PBS (blank control); (2) PBS + laser (laser control); (3) PCNH (non-targeted nanoparticle control); (4) PCNH + laser (non-targeted phototherapy control); (5) TRPV2–PCNH (targeted nanoparticle control) and (6) TRPV2–PCNH + laser (targeted phototherapy) groups. Here, TRPV2 is linked to neoplasm.