TRPV2 and neoplasm: Consistent with the inactivated β-catenin function, RT-qPCR analyses of downstream targets of β-catenin signalling pathway also showed that, after laser irradiation, all target genes were significantly down-regulated in TRPV2 overexpressing cells and tumours pretreated with TRPV2–PCNH nanoparticles (Fig. 7d, e).