DAB2 and neoplasm: These findings suggest (i) the positive correlations between CXCL8 or DAB2 and SOCS1 or SOCS3 observed in the TCGA-LIHC dataset likely results from deregulated signaling pathways in the tumor tissues and (ii) the elevated CXCL8 expression worsens the prognosis of cases with low SOCS1 or SOCS3 expression as CXCL8 is implicated in promoting tumor angiogenesis [42].