CRP and otitis media: The best model fit for antibiotic use at any time point was achieved for the following factors (c-index 0.916) (Table 3): otitis media (odds ratio 8.33; 95% confidence interval 3.58–19.37), peak CRP (OR 1.77; 95% CI 1.54–2.04), and the length of oxygen therapy (OR 1.40; 95% CI 1.13–1.74).