PTK2 and endometrial carcinoma: Moreover, Zhou et al. [15] reported a correlated over-expression of methyltransferase EZH2, FAK and 397 tyrosine-phosphorylated form of FAK in endometrial carcinomas, which was associated with high histologic grade, angiolymphatic invasion, lymph node metastasis, myometrial invasion, and cervical involvement, thus predicting a more aggressive behavior.