Even if the OATP2B1-935A variant is assumed to exhibit reduced transport function [70], Mostaghel et al. [40] report higher mean tissue abiraterone levels in carriers of the rs12422149 AA/AG genotype as compared to prostate cancer tissue of individuals with homozygosity for the wildtype allele. This evidence concerns the gene SLCO2B1 and Familial prostate cancer.