TSLP and psoriasis: As for the regulation of S100 gene families, studies reported the upregulation of IL-17-induced psoriasis-associated genes including S100A7 via IκBζ, downregulation of S100A7 by thymic stromal lymphopoietin (TSLP), binding of CCAAT/enhancer binding protein β (C/EBPβ) to the promoter region of S100A8, and the induction of S100SA2 protein, an important regulator of keratinocyte differentiation, by p53 tumor suppressor protein.