In the current study, VPA altered the expression of 11 proteins implicated in Alzheimer’s disease (ATP5A1, ATP5B, ATP5D, ATP5F1, ATP5J, SDHA, SDHB, UQCRB, UQCRC1, UQCRC2, and UQCRH), while 16 proteins implicated in Parkinson’s disease (ATP5A1, ATP5B, ATP5D, ATP5F1, ATP5J, SDHA, SDHB, SLC25A6, UBA7, UQCRB, UQCRC1, UQCRC2, UQCRFS1, UQCRH, VDAC1, and VDAC3). The gene discussed is SDHB; the disease is early-onset autosomal dominant Alzheimer disease.