We found that each 1-year increase in age (OR, 1.057; 95% CI, 1.018-1.098; P=0.004), Wuhan exposure history greater than 2 weeks (OR, 2.765; 95% CI, 1.040-7.355; P=0.042), CKD (OR, 6.966; 95% CI, 1.310-37.058; P = 0.023), diarrhea (OR, 24.349; 95% CI, 3.580-165.609; P=0.001), Myoglobin higher than 106 μg/L (OR, 8.910; 95% CI, 1.225-64.816; P=0.031), WBC higher than 10×109/L (OR, 5.776; 95% CI, 1.052-31.722; P=0.044), and CRP higher than 10 mg/L (OR, 5.362; 95% CI, 1.631-17.626; P=0.006) were independent risk factors for severe cases (Table 4). The gene discussed is CRP; the disease is chronic kidney disease.