For one unit increase in natural log-transformed TNF levels, the ORs were 2.25 (95% CI, 1.50, 3.37) for coronary artery disease, 2.27 (95% CI, 1.50, 3.43) for ischaemic stroke, 0.54 (95% CI, 0.42, 0.96) for overall cancer, 0.51 (95% CI, 0.39, 0.67) for breast cancer, and 0.20 (95% CI, 0.09, 0.45) for colorectal cancer. Here, TNF is linked to colorectal cancer.