The pathway with the most proteins identified from the group of 23 proteins was Inflammation mediated by cytokine and cytokine signaling (P00031, Fractalkine, MIP-1a and RANTES), and six additional pathways were identified: Alzheimer disease-presenilin (P00004, E-cadherin), Apoptosis signaling (P00006, FASL), CCKR signaling (P06959, E-cadherin), Cadherin signaling (P00012, E-cadherin), FAS signaling (P00020, FASL) and Wnt signaling (P00057, E-cadherin). This evidence concerns the gene CDH1 and early-onset autosomal dominant Alzheimer disease.