Fourteen different proteins mapped to 11 different pathways, pathological pathways include: Apoptosis signaling pathway (P00006, TNF-R2, FASL, Granzyme B) and FAS signaling pathway (P00020, FASL) and Alzheimer disease-presenilin pathway (P00004, E-Cadherin). The gene discussed is FAS; the disease is early-onset autosomal dominant Alzheimer disease.