Initially, the authors showed that APOE*E4/*E4 homozygotes were more likely to be SARS-CoV-2 positive when compared to APOE*E3/*E3 homozygotes, regardless of presence of APOE*E4-associated diseases (dementia, hypertension, coronary artery disease, type 2 diabetes) (1). Here, APOE is linked to Hypertension.