Prospective studies with stringent diagnostic criteria as recommended by the Fourth International Workshop on the Management of Asymptomatic Primary Hyperparathyroidism (ie, repeated measurements of albumin‐corrected and ionized Ca over 3 to 6 months) will be necessary to elucidate the real impact of NHPT on the onset and progression of renal, bone, and nontraditional manifestations of this disorder. This evidence concerns the gene ALB and primary hyperparathyroidism.