CRC tumorigenesis can be driven by specific molecular alterations with functional effects in prosurvival signaling pathways such as p53 pathway, Wnt-β-catenin pathway, EGFR- (epidermal growth factor receptor-) MAPK (mitogen-activated protein kinase) pathway, PI3K (phosphatidylinositol 3-kinase) pathway, nuclear factor-kappa B (NF-κB) pathway, and activator protein 1 (AP-1) pathway [5]. Here, EGFR is linked to colorectal carcinoma.