Our findings demonstrated that Foxp3+ γδ T cells express a high-level of TIGIT and DNAM-1 and a high TIGIT/DNAM-1 ratio in Foxp3+ γδ T cells, which leads to better understanding of the TIGIT/DNAM-1 axis on γδ Treg cells in AML patients. This evidence concerns the gene CD226 and acute myeloid leukemia.