We next investigated the frequency and expression pattern of DNAM-1 on Foxp3+ γδ T cells and found a higher level of DNAM-1 expression in the AML-NR and de novo AML groups compared to the AML-CR and HI groups with the pattern AML-NR (median: 5.27%, range: 2.70%-14.90%) > de novo AML (median: 2.68%, range: 0.45%-27.30%) > HI (median: 1.63%, range: 0.17%-5.74%) > AML-CR (median: 1.30%, range: 0.04%-5.37%; NR vs. de novo, P = 0.035; NR vs. CR, P ≤ 0.001; NR vs. HI, P ≤ 0.001; de novo vs. CR, P = 0.002; de novo vs. HI, P = 0.005) (Figures 2(a) and 2(b)). The gene discussed is CD226; the disease is acute myeloid leukemia.