Strikingly, we observed that AML patients with high expression of TIGIT+Foxp3+ γδ T cell subsets correlated with poor OS (TIGIT+Foxp3+high vs. TIGIT+Foxp3+low, 12-month OS 34% vs. 63%, P = 0.049) (Figure 3(d)). This evidence concerns the gene TIGIT and acute myeloid leukemia.