Chen et al. have shown that nsPEF ablation in N1-S1 HCC orthotopic model rats yields a response rate of 80–90%; nsPEF eliminates N1-S1 HCC tumors and protects against recurrences for up to 20 weeks by inducing the infiltration of granzyme B-expressing T-cells/NK cells [12]. The gene discussed is GZMB; the disease is hepatocellular carcinoma.