MTOR and cancer: To help answer these questions, other studies have shown that the secretome from BMSCs induces tumorigenesis in an in vivo and in vitro mouse model through activation of mTOR [31], whereas ADSCs and their conditioned media inhibit cancer growth using in vivo and in vitro mouse models [32], suggesting that ADSCs are a better cell choice for therapeutic development than are BMSCs in terms of tumorigenesis.