SOD1 and metabolic syndrome: The current results revealed that no significant changes in MDA, SOD, CAT, and GSH-Px activities were observed in the prefrontal cortex of MetS rats with the sham operation which received vehicle, whereas significantly decreased SOD, CAT, and GSH-Px activities and an increased MDA level were observed in MetS rats with MCAO as shown in Table 1 (p value < 0.01, 0.01, 0.001, and 0.001, respectively; compared to the HCHF+sham operation+vehicle group).