Clinically, we validated that the expression levels of SWELL1 were significantly associated with those of PTGES2 (Pearson correlation: R = 0.7609) or GGT5 (R = 0.67) or SCD1 (R = 0.8103) in HCC tissues (Figure 4F and Figure S5F). Here, PTGES2 is linked to hepatocellular carcinoma.