The analysis of a publicly available HCC patient data from The Cancer Genome Atlas (TCGA) in liver cancers revealed that SWELL1 was an important factor of evaluating risk of mortality and Diagnosis Related Grading (DRG) of HCC patients, in which the up-regulation of SWELL1 was observed in every stage of HCC patients (Figure 1B). Here, LRRC8A is linked to hepatocellular carcinoma.