NUCLEOLIN and colorectal cancer: Next, we observed that high NCL expression was associated with poor prognosis, such as low disease-free survival, in patients with breast and colorectal cancer (Bertucci and Sveen dataset from 'R2: Genomics Analysis and Visualization platform (http://r2.amc.nl)'; Figure 4B), which is consistent with a previous report showing that high NCL expression serves as a poor prognostic marker in patients with breast and colorectal cancer 26,27.