For example, the majority of ingredients in ATR, such as ATR6, ATR19, ATR30, ATR54, and ATR93, exhibited strong activation of the neurotransmitter receptors CHRM1, CHRM2, CHRM2, GABRA1, and GABRA2, modulating neurotransmission dysfunction in the AD brain [73, 74]. The gene discussed is ATR; the disease is Alzheimer disease.