IL1B and cancer: 564 studies were excluded for at least one of the following reasons after title and abstract were screened: (1) the intervention did not include acupuncture; (2) the stimulation site was not at the acupoint; (3) the model was not cancer-induced bone pain; (4) they were not animal studies; (5) they were reviews or case reports or letters; (6) the outcomes did not include PWT/PWL/BW/GFAP/IL-1β; and (7) they did not include a usual-care and/or placebo comparison group.