It is important to recognize that other species of TDP-43 CTFs have been identified at 15-16 kDa, 22-25 kDa, and 33-37 kDa in ALS/ALS-FTLD, however due to low levels of reporting their prevalence in disease remains elusive [56, 74, 75, 81–85]. This evidence concerns the gene TARDBP and amyotrophic lateral sclerosis.