The baseline level of plasma angiopoietin-2 was median 1261.8 pg/mL (IQR 1018.6–1579.6, range 967.5–1802.1) in stage III and IV cancer and 987.9 pg/mL (IQR 883.9–1303.8, range 813.7–1499.1) in stage I and II cancer (Mann-Whitney U test, p = 0.2556). Here, ANGPT2 is linked to cancer.