Additionally, many significant CpGs mapped to the same gene, suggestive of differentially methylated regions (DMRs); these included POUF6 (6 CpGs), PRDM8 (4 CpGs), SNRPN (4 CpGs), and RASGEF1C (3 CpGs) associated with the ADHD subset, and NINJ2 (5 CpGs), PRKG1 (4 CpGs) and CES1 (2 CpGs) associated with the OCD subset (example DMRs shown in Fig. 2). The gene discussed is PRDM8; the disease is attention deficit-hyperactivity disorder.