DEPs in Pengxian yellow chickens and Tibetan chickens after ALV-J infection were involved in viral myocarditis, Th1 and Th2 cell differentiation, MAPK signaling pathway, inflammatory bowel disease, HTLV-I infection, graft-versus-host disease, autoimmune thyroid disease, and antigen processing and presentation such as BLBII, BF2, CREBBP, and NCOR1 (Table 5) (Figure 11 (C)). This evidence concerns the gene CREBBP and autoimmune thyroid disease.