DEPs in infected with ALV-J groups and control groups of Pengxian yellow chickens were involved in viral myocarditis, staphylococcus aureus infection, NFκB signaling pathway, intestinal immune network for IgA production, hematopoietic cell lineage, and autoimmune thyroid disease, such as KDM5A and RAB44 (Table 4) (Figure 8 (B)). The gene discussed is NFKB1; the disease is autoimmune thyroid disease.