DEPs in infected with ALV-J groups and control groups of Avian broilers were involved in transcriptional misregulation in cancer, salivary secretion, prion diseases, endocrine resistance, breast cancer, and asthma such as CDC42SE2, XRN1, MKI67, and RAB44 (Table 4) (Figure 8 (A)). The gene discussed is XRN1; the disease is cancer.