DEPs in Avian broilers and Tibetan chickens after ALV-J infection were involved in viral myocarditis, transcriptional misregulation in cancer, intestinal immune network for IgA production, B arterials invasion of epithelial cells and autoimmune thyroid disease such as ANKRD27, HSPG, RELA, and ZNF148 (Table 5) (Figure 11 (B)). This evidence concerns the gene ANKRD27 and autoimmune thyroid disease.