DEPs in Avian broilers and Tibetan chickens after ALV-J infection were involved in viral myocarditis, transcriptional misregulation in cancer, intestinal immune network for IgA production, B arterials invasion of epithelial cells and autoimmune thyroid disease such as ANKRD27, HSPG, RELA, and ZNF148 (Table 5) (Figure 11 (B)). The gene discussed is CD79A; the disease is autoimmune thyroid disease.