The SNPs rs548234 (Han Chinese)95 and rs6568431 (European)96 predispose females to the development of SLE, and are both located in the intergenic region between PRDM1 and ATG5. Further analysis of the Han Chinese SNP revealed that DCs, but not B‐cells, show lower Blimp‐1 expression in individuals carrying the risk allele,81 while ATG5 expression was unchanged. This evidence concerns the gene ATG5 and systemic lupus erythematosus.