PRDM1 and systemic lupus erythematosus: Interestingly, the SNP induces binding of the transcriptional repressor KLF4 (kruppel‐like factor 4), which is expressed at high levels in DCs, providing a mechanistic explanation for why alterations in Blimp‐1 levels are specific to DCs, and cementing the finding that dysregulation of DCs, caused by low Blimp‐1 expression, can lead to SLE.81