Two close homologues within this family, ZIP6 (SLC39A6, also known as LIV-1) and ZIP10 (SLC39A10) [27, 28], with a 43.5% sequence identity, are on the same clade of the ZIP family phylogenetic tree [29] and have both been independently implicated in cancer [23, 29]. The gene discussed is SLC39A6; the disease is cancer.