Finally our analysis also revealed Trpv3, but not the Trpv1, Trpv2, or Trpv4 genes, and two genes involved in migraine, namely Atp1a2 and Scn1a (mutations of which are responsible for familial hemiplegic migraine types 2 and 3 respectively)45. Here, SCN1A is linked to familial or sporadic hemiplegic migraine.