The reciprocal relationship between miR-382 and PTEN has been reported in acute promyelocytic leukemia, infantile hemangioma, and liver regeneration27,29,44 In our study, we performed a dual-luciferase reporter assay, which confirmed that miR-382 negatively regulated PTEN by combining the 3′UTR of gene pten in 293T cells. This evidence concerns the gene PTEN and capillary hemangioma.