Among these cell lines, HT29 cell line was highly expressed with FBX8, SOX-2 and SOX-2, and CD44, while quite weakly expressed with CDK4, HIF-1α, and c-Myc (Supplementary Fig. S2A), indicating that HT29 cell line was an appropriate model to study tumor dormancy. The gene discussed is CDK4; the disease is neoplasm.