It has been claimed that genetic components (e.g., polymorphisms in matrix metallopeptidase 16 (MMP16) and SPARC (Osteonectin) Cwcv and Kazal like domains proteoglycan 2 (SPOCK2) could play a role regarding the susceptibility for BPD [75]. The gene discussed is MMP16; the disease is bronchopulmonary dysplasia.