CTLA4 and hypophysitis: Caturegli et al. confirmed the expression of CTLA-4 in pituitary cells in an autopsy series of patients who received anti-CTLA-4 antibodies and a higher level of pituitary CTLA-4 expression in a patient with clinical and histological evidence of severe hypophysitis also associated with T-cell infiltration and IgG-dependent complement fixation and phagocytosis.