These are decorin, which binds with high affinity to the EGFR [367], causing downregulation of kinase activity and blocking intracellular calcium mobilization and thereby acting as tumor suppressor [367,368,369], tenascin C [370], the γ2 chain of laminin-332 [371], thrombospondin-1 [372] and fibulin-3 [373]. The gene discussed is EGFR; the disease is neoplasm.