We found that the ZNF554 log2 expression level was lower in all glioma groups (ODG grade II: 7.673 ± 0.027, ODG grade III: 7.659 ± 0.030, AC grade II: 7.579 ± 0.029, AC grade III: 7.458 ± 0.027, GBM: 7.241 ± 0.035, p < 0.001 in all cases) compared to controls (8.272 ± 0.161, Figure 2A). This evidence concerns the gene ZNF554 and central nervous system cancer.