In ACs, the average ZNF554 immunoscores were 40% and 52% lower in grade III and grade IV tumors, respectively, than in controls (control: 3.00 ± 0.00; anaplastic AC grade III: 1.80 ± 0.29, p < 0.05; GBM grade IV: 1.45 ± 0.25, p < 0.01, Figure 1A,B). The gene discussed is ZNF554; the disease is glioblastoma.