INS and prediabetes syndrome: Other studies confirmed the association of serum myostatin with dysglycemia; the circulating myostatin concentration was found to be higher in prediabetes and the highest in type 2 diabetes mellitus in comparison with healthy controls [150], and it was correlated with fasting plasma glucose, HOMA-IR (Homeostatic Model Assessment for Insulin Resistance), the area under curve for insulin during the oral glucose tolerance test, insulin sensitivity index and serum immunoreactive insulin levels [148,150,151].