From those two partial response cases in this subgroup, we observed that tumor-specific T cells effectively infiltrated and removed tumor cells upon ICB treatment when patients with activated NK cells (i.e., high level of NKp46) had both high expression of IFNγ from activated T cells (i.e., high level of PD-1 and CXCR3) and PD-L1 and CXCL9 from tumors (high level of IFNγ receptor). The gene discussed is CXCL9; the disease is neoplasm.