For the representative values of the expression levels of genes in the type I IFN pathway and antigen-presenting machinery, we selected three genes (IFI16, MYD88, and JAK2) from the type I IFN pathway and four genes (TAP1, TAP2, PSMB9, and HLA-DQA1) from the antigen-presenting machinery and termed this group as a tumor-intrinsic classifier (TIC). The gene discussed is IFI16; the disease is neoplasm.