IMPDH1 and Alzheimer disease: Cystoid macular edema (CME) was observed in 4 patients (P2-RPGR) (Figure 4, A), P11-IMPDH1, P13-IMPDH1 (Figure 4, D), and P26-RHO (Figure 4, F), with 1 having XL (P2) and 3 having AD modes (P11, P13, P26) inheritance mode.