ABCG2 and cancer: The top five significantly enriched KEGG pathway by DEGs in LS were lysine degradation, choline metabolism in cancer, phospholipase D signaling pathway, Fc gamma R-mediated phagocytosis and sphingolipid signaling pathway, while only three KEGG pathways (ECM-receptor interaction, ABC transporters and mRNA surveillance pathway) were enriched by the DEGs in HS.