A recent study also confirmed that inhibition of either CD162 or CD44 on human monocytic leukemia U937 cell line did not alter rolling on E-selectin, whereas knockdown of both CD162 and CD44 increased rolling velocity and reduced U937 adhesion to immobilized E-selectin under flow conditions by about 40% (Spertini et al., 2019). This evidence concerns the gene SELPLG and monocytic leukemia.