TNF and neoplasm: Secretion of different proinflammatory molecules in the tumor sites, including IFN-γ, TNF-α, IL-6, IL-8, TGF-β, hepatocyte growth factor, platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), and CXCL12 and some other chemoattractant molecules (Seo et al., 2011), prompts circulating MSCs to migrate to tumor sites (D’Souza et al., 2013).