In uninfected mice and at 8 h post-infection, there was significantly inhibition of the Serine Protease Inhibitor Kazal type 1 (SPINK1) pancreatic cancer pathway in the gastric tissue of Muc1−/− mice compared with WT mice uninfected or at 8 h post-infection (P = 6.08E-14 and P = 2.25E-19, respectively, Figure 5), but at 24 and 72 h post-infection, we detected a strong activation of this pathway in Muc1−/− mice (P = 1.38E-22 and P = 5.87E-13, respectively, Figure 5). This evidence concerns the gene SPINK1 and familial pancreatic carcinoma.