Considering FAB classification, we also observed a significant association between a reduction in mRNA expression level of TAS2R10 (adjust BH p-value = 0.007), TAS2R5 (adjust BH p-value = 0.03), and TAS2R14 (adjust BH p-value = 0.045) and a more differentiated status of AML blast (Figure 2E). The gene discussed is TAS2R5; the disease is acute myeloid leukemia.