CDKN1B and cancer: Results of the cancer and signaling antibody arrays showed that tumors presented a significant increase in the expression of proliferative cell nuclear antigen (PCNA), p27Kip1, N-cadherin, HIF-1α, Stat-3, Akt-S473, AMPka, mTOR-S2448, HSP27, Bad, PRAS40, SAPK/JNK, and caspase-3 (Figures 5A–C), which were significantly recovered/diminished in their expression/phosphorylation level by CDP treatment.