From this IRG–TF regulatory network, we can see that in cervical cancer, FOXP3 positively regulates low-risk IRGs (LTA and PTPN6) and positively regulates low-risk IRGs (LTA) in endometrial cancer, suggesting that FOXP3 may act as a tumor suppressor in these two types of cancers. This evidence concerns the gene PTPN6 and cancer.