The cytokine profile of COVID-19 patients with differences in disease severity has been investigated, and a subset of patients with severe COVID-19 develop profound inflammation and multiorgan dysfunction that is consistent with a “cytokine storm.” Recently, a large panel of cytokines (IFN-γ, TNF-α, IL-2, IL-4, IL-6, and IL-10) and C-reactive protein (CRP) have been analyzed and compared with serum samples from a control group and from COVID-19 patients. The gene discussed is IL4; the disease is COVID-19.