The patients with PBC also showed a markedly increased percentage of CD8+TIGIT+ T cells than the DCs (60.0 ± 15.60 vs. 46.44 ± 15.85, p = 0.011) and HCs (60.0 ± 15.60 vs. 41.73 ± 12.92, p < 0.001) (Figure 1B). This evidence concerns the gene CD8A and primary biliary cholangitis.