If IL-4 protein production is confirmed, it is of interest to assess whether this IL-4 production reflects either: tissue-specific differences among nILC2 cells in the lung and intestine; helminth-specific differences related to infection by N. brasiliensis or H. polygyrus; or reflects an intestinal iILC2 population that maintains IL-4 protein production throughout the course of H. polygyrus infection. Here, IL4 is linked to infection.